Powerful speeches and statements of unity have dominated the 75th Golden Globe awards.
It was the first major Hollywood awards ceremony since the film industry was hit by sexual harassment scandals, with stars wearing black to honour victims.
Oprah Winfrey summed up the mood, saying "a new day is on the horizon" as she collected an honorary award.
The big film winner of the night was Three Billboards Outside Ebbing, Missouri, which took home four awards.
It won the best film drama award, with its star Frances McDormand also picking up a trophy for best actress.
The Oscar-winning actress stars as a grieving mother who challenges police over the fact her daughter's killer has not been found.
Big Little Lies won the most awards in the television categories, including honours for its stars Nicole Kidman, Laura Dern and Alexander Skarsgard. It was also named best limited TV series.
'Power of women'
Kidman won the first award of the night for her role as a victim of domestic violence.
She dedicated her win to her castmates, daughters and mother, saying: "Wow, the power of women."
The Golden Globes are organised by the Hollywood Foreign Press Association and are seen as an indicator of which films are likely to do well at the Oscars, which take place on 4 March.
The main focus on the night was on the current atmosphere in Hollywood and campaigns like Me Too and Time's Up, which are focused on bringing about change for women not only in the entertainment industry but also around the world.
Many winners and presenters at the Beverly Hills ceremony addressed the ongoing scandal - with host Seth Meyers setting the tone with his opening monologue.
"Welcome ladies and remaining gentlemen," he told the gathered stars of film and TV, before saying: "It's 2018 and marijuana is finally allowed and sexual harassment finally isn't.
"For the male nominees in the room tonight, this is the first time in three months it won't be terrifying to hear your name read out loud."
It was Oprah whose speech had the biggest reaction, with stars applauding and rising to their feet.
Speaking as she was awarded the honorary Cecil B DeMille trophy - the first black woman to get the honour - she said: "Speaking your truth is the most powerful tool we all have.
"For too long, women have not been heard or believed if they dare speak the truth to the power of those men. But their time is up. Their time is up!"
The theme was echoed by Laura Dern, winner of a best supporting actress for Big Little Lies, who said: "Many of us were taught not to tattle.
"It was a culture of silencing, and that was normalised... May we teach our children that speaking out without the fear of retribution is our culture's new North Star."
Barbra Streisand used her presenting slot to express outrage that she remains the only woman to win the best director award at the ceremony - and that was back in 1984.
"Folks, time's up," she said. "We need more women directors and more women to be nominated for best director."
Greta Gerwig, whose directorial debut Lady Bird was named best musical or comedy film, could be seen being hugged by her film's star, Saoirse Ronan, as Streisand made her comments.
Gerwig was not nominated in the directing category - an award won by The Shape of Water's Guillermo del Toro - but neither was any woman.
It was a fact that did not escape Natalie Portman's notice as she presented the best director award, pointedly referring to the "all male nominees".
In the TV categories, The Handmaid's Tale and The Marvelous Mrs Maisel did well, with two awards each.
Elisabeth Moss, named best actress in a TV drama for The Handmaid's Tale, dedicated her win to author Margaret Atwood, whose book is the source material for the series.
After reading a quote from Atwood, she told the audience: "We no longer live in the gaps... we are the story in print and we are writing the story ourselves."
They were apt words for a night when Hollywood seemed determined to turn a new page.
Golden Globes 2018: Full list of winners
All the winners at the 75th annual Golden Globe Awards, held in Los Angeles on 7 January 2018.
Best motion picture - drama
Three Billboards Outside Ebbing, Missouri
Best performance by an actor in a motion picture - drama
Gary Oldman, Darkest Hour
Best performance by an actress in a motion picture - drama
Frances McDormand, Three Billboards Outside Ebbing, Missouri
Best performance by an actor in a motion picture - comedy or musical
James Franco, The Disaster Artist
Best performance by an actress in a motion picture - comedy or musical
Saoirse Ronan, Lady Bird
Best performance by an actor in a supporting role in a motion picture
Sam Rockwell, Three Billboards Outside Ebbing, Missouri
Best performance by an actress in a supporting role in a motion picture
Alison Janney, I, Tonya
Best director - motion picture
Guillermo del Toro, The Shape of Water
Best screenplay - motion picture
Martin McDonagh, Three Billboards Outside Ebbing, Missouri
Best animated film
Best foreign language film
In the Fade
Best original score - motion picture
The Shape of Water
Best original song - motion picture
This Is Me - The Greatest Showman
Best television series - drama
The Handmaid's Tale
Best television series - comedy
The Marvelous Mrs Maisel
Best actor in a television series - drama
Sterling K Brown, This is Us
Best actress in a television series - drama
Elisabeth Moss, The Handmaid's Tale
Best actor in a television series - musical or comedy
Aziz Ansari, Master of None
Best actress in a television series - musical or comedy:
Rachel Brosnahan, The Marvelous Mrs Maisel
Best television limited series or motion picture made for television:
Big Little Lies
Best actor in a limited series or motion picture made for television:
Ewan McGregor, Fargo
Best actress in a limited series or motion picture made for television:
Nicole Kidman, Big Little Lies
Best supporting actor in a series, limited series or motion picture made for television:
Alexander Skarsgard, Big Little Lies
Best supporting actress in a series, limited series or motion picture made for television:
Laura Dern, Big Little Lies.